States looking to ban titanium dioxide as a food additive

Another common use of titanium IV oxide is in food coloring. Titanium dioxide is a FDA-approved food additive that is used to enhance the color of various food products. It is commonly used in candies, pastries, and dairy products to create vibrant colors. Titanium dioxide is a safe food additive that is used in small quantities to enhance the visual appeal of food products.
Skittles has been making headlines in recent weeks and not because a new flavor has been added to the popular taste the rainbow candy.

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But in the U.S., titanium dioxide is found all over the grocery shelves. Candy like Skittles, Starbursts, and Jell-O, gum like Trident White peppermint gum and Mentos Freshmint Gum, cake products like Duncan Hines Creamy Vanilla Frosting, and Nabisco Chips Ahoy! cookies are just a few of the myriad food items that contain the additive.
Yet another study, this one published in 2006 by the International Agency for Research on Cancer said there was insufficient evidence to conclude that titanium dioxide causes cancer. However, the study also categorized the ingredient as a potential human carcinogen.
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In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2. With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”
Reason for listing: CNNC Huayuan Titanium Dioxide Co., Ltd., a well-known brand of titanium dioxide factory, started in 1989, specializing in the research and development, production, sales and service of titanium dioxide products. One of the titanium dioxide enterprises producing more than 10,000 tons.
In India, purchasers took a wait-and-see strategy because of the concerns about an unpredictable demand pattern following the second wave of the pandemic around the end of September. Whereas in China, producers were heard operating at optimal rates even though export orders were low in July.
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