In the UK it was submitted by Dow (who manufacture HPMC for the global food market) for approval to the Advisory Committee on Novel Foods and Processes in November 2011.

redispersible polymer powder hs code. It enhances the performance of these products by providing better adhesion, water resistance, and flexibility. The powder can be easily dispersed in water to form a stable emulsion, making it easy to use in various formulations.
In the rabbit hindgut, fermentation occurs through a wide prevalence of Bacteroides that do not allow an extended digestibility of fibre. Digestibility of cellulose was shown to amount to 16% of the administered dose, whereas values of 14% and 18% were reported for fibre (cellulose being the main component) (review from the NRC, 1977). Later studies reported values comprised between 15 and 25% in rabbits administered different plant sources of cellulose (Gidenne and Perez, 1996; Chiou et al., 1998). In the horse, digestion of plant structural carbohydrates (including cellulose) occurs in the hindgut (colon and overall caecum). The microbiota of the caecum comprises bacteria similar to those of the rumen, but specific protozoa. The resulting digestibility is about two-third that measured in ruminants.
In supplements, HPMC is often combined with other ingredients such as vitamins, minerals, plant extracts, and amino acids. While HPMC itself is unlikely to interact with these ingredients, potential interactions between other components of the supplement must be considered. For example, certain vitamins or minerals may interact with medications or other supplements, causing adverse reactions or reduced effectiveness.

2 Data and methodologies
Examples: Gonak; Goniosol; Lacril; Methocel [Dow]; Ultra Tears