2)Applying another layer on top before the underlying layer has dried, which can also lead to bubbling.
Methyl cellulose and HPMC are two types of cellulose-based polymers commonly used in building materials. However, Methyl Cellulose is gradually being replaced by HPMC due to the higher requirements in modern construction. In addition, some suppliers refer to methyl cellulose as the common name for hydroxypropyl methyl cellulose (HPMC) and Hydroxyethyl methyl cellulose (HEMC). We will explore the difference between HPMC and HEMC in later articles.
EFSA has verified the European Union Reference Laboratory (EURL) report as it relates to the methods used for the control of HPMC in animal feed. The Executive Summary of the EURL report can be found in Annex A.6

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With a busy life and little time this isn’t always possible.
This makes a loaf more akin to gluten containing bread
The majority of the available studies have been performed in rats, just few of them in rabbits and dogs. Among those meeting the current criteria for toxicological testing, the no observed adverse effect level (NOAEL) values for the different modified celluloses were identified most often corresponding to the highest tested level or changes in body or organ weights. For microcrystalline cellulose (E 460) the identified NOAELs in rats ranged from 3,769 mg/kg body weight (bw) per day to 9,000 mg/kg bw per day and in all cases corresponded to the highest levels of the test substance. For methyl cellulose (E 461), the dose level of 3% in rats (equivalent to 2,700 mg/kw bw per day) was selected as the NOAEL based on a decrease in body and organ weight displayed in male rats administered with the top additive level (10%, equivalent to 9,000 mg/kg bw per day and day).