Although the evidence for general toxic effects was not conclusive, on the basis of the new data and strengthened methods we could not rule out a concern for genotoxicity and consequently we could not establish a safe level for daily intake of the food additive, commented Matthew Wright, member of the EFSA's Food Additives and Flavourings Panel in a press statement.
According to a 2011 study published in Radiology and Oncology, titanium dioxide may lead to some adverse effects in the body, including oxidative stress, inflammation, and changes in cell signaling pathways. Additionally, pure titanium dioxide can be notably harmful when inhaled.
With 30% of the world's lithopone factories located in China, the country has become a major player in the global lithopone market. Chinese manufacturers are able to produce lithopone at a competitive price, making it an attractive option for companies looking to reduce their production costs. In addition, China's large production capacity ensures a steady and reliable supply of lithopone to markets around the world.
lithopone 30% factories

Wholesale Iron Oxide Yellowred Blue Green Concrete Cement Add Color
Titanium dioxide has similar uses in non-food products. It is used in sunscreen as effective protection against UVA/UVB rays from the sun, which creates a physical barrier between the sun’s rays and the skin. It’s also used to whiten paint, paper, plastic, ink, rubber, and cosmetics.
Lithopone B311

excellent white tio2 supplier. The production of TiO2 can have significant environmental impacts, so it is crucial to work with a supplier that prioritizes sustainable practices and minimizes their environmental footprint. An excellent white TiO2 supplier will have certifications and initiatives in place to demonstrate their commitment to sustainability and responsible sourcing.


CAS NO. :
Genotoxicity refers to the ability of a chemical substance to damage DNA , the genetic material of cells. As genotoxicity may lead to carcinogenic effects, it is essential to assess the potential genotoxic effect of a substance to conclude on its safety.
Lithopone was discovered in the 1870s by DuPont. It was manufactured by Krebs Pigments and Chemical Company and other companies.[2] The material came in different seals, which varied in the content of zinc sulfide. Gold seal and Bronze seals contain 40-50% zinc sulfide, offering more hiding power and strength.[3] Although its popularity peaked around 1920, approximately 223,352 tons were produced in 1990. It is mainly used in paints, putty, and in plastics.[1]
Health Canada's Food Directorate recently completed a “state of the science” report on titanium dioxide (TiO2) as a food additive. Food-grade TiO2 is a white powder made up of small particles that has been permitted in Canada and internationally for many years as a food additive to whiten or brighten foods. Food-grade TiO2 has long been considered safe in Canada and in other countries when eaten as part of the diet.
However, they did find that minor levels of 0.01% were absorbed by immune cells — known as gut-associated lymphoid tissue — and may be delivered to other organs. Currently, it’s unknown how this may affect human health (17Trusted Source).
Neutral White, 26 per cent zinc sulphide, 66 per cent barium sulphate, 5 per cent infusorial earth, 3 per cent whiting.
Because of their small size, nanoparticles may have unique physical and chemical properties. These properties may cause them to interact with living systems differently than larger materials with the same chemical composition (also known as bulk materials).
CAS NO. :
The company was established in 1989. Its predecessor is the titanium dioxide factory, a secondary independent accounting production unit affiliated to CNNC 404. It is a high-grade rutile with an annual output of more than 10,000 tons that imported advanced foreign technology and key equipment earlier in my country. It is also a high-quality titanium dioxide supplier in my country earlier in the market. After years of development, the company now has three production bases in Jiayuguan, Gansu, Baiyin, and Maanshan, Anhui.
Although barium sulfate is almost completely inert, zinc sulfide degrades upon exposure to UV light, leading to darkening of the pigment. The severity of this UV reaction is dependent on a combination of two factors; how much zinc sulfide makes up the pigments formulation, and its total accumulated UV exposure. Depending on these factors Lithopone B301, Lithopone B311 powder itself may vary in shade over time, ranging from pure white all the way to grey or even black. To suppress this effect, a dopant might be used, like small amount of cobalt salts, which would be added to the formulation. This process creates cobalt-doped zinc sulfide. The cobalt salts help to stabilize zinc sulfide so it will not have as severe a reaction to UV exposure.

Overall, the Food Directorate's comprehensive review of the available science of TiO2 as a food additive showed:
In addition to its strength and UV resistance, nano titanium dioxide also has excellent optical properties. This makes it an ideal material for use in pigments and coatings, as it can help create vibrant colors and enhance the appearance of a wide range of products. Our nano titanium dioxide products are carefully formulated to ensure that they provide the best possible optical properties, so customers can achieve the look they desire.
Funding sources
The Market Dynamics of Wholesale Titanium Dioxide
In a 2019 study published in the journal Nanotoxicology, researchers recreated the first phase of digestion in mice and fed them titanium dioxide, then examined whether accumulation occurred in the organs. Researchers wrote: “Significant accumulation of titanium was observed in the liver and intestine of E171-fed mice; in the latter a threefold increase in the number of TiO2 particles was also measured. Titanium accumulation in the liver was associated with necroinflammatory foci containing tissue monocytes/macrophages. Three days after the last dose, increased superoxide production and inflammation were observed in the stomach and intestine. Overall, [this] indicates that the risk for human health associated with dietary exposure to E171 needs to be carefully considered.”
In conclusion, the TiO2 industry supplier is an essential part of the supply chain for many industries that rely on this versatile pigment. By staying informed about market trends, investing in sustainable practices, and continuously improving their operations, TiO2 suppliers can continue to meet the growing demand for this essential material.