Titanium dioxide comes in the form of a white powder and is sometimes used in cosmetics to adjust a color to a lighter shade. This is also why it can produce a white cast.

Journal Information

Exposure routes are the pathways that allow ingredients to enter our bodies. Primary exposure routes include: 

CONSEILS D'EMPLOI

Often used as a glaze for ceramics, titanium dioxide provides a bright, glossy finish and improves the durability and stain resistance of ceramic products.

A study published in the Journal of Agricultural and Food Chemistry in 2019 sought to examine the effects of titanium dioxide on intestinal inflammation. Researchers did this by feeding rats titanium dioxide nanoparticles and found that, after the course of two to three months, the animals had lower body weights and induced intestinal inflammation. The researchers also found the nanoparticles altered gut microbiota composition and aggravated chronic colitis. The rats also experienced reduced populations of CD4+T cells (which are cells that help organize immune responses by prompting other immune cells to fight infection), regulatory T cells, and white blood cells in mesenteric lymph nodes. The researchers wrote: “Dietary TiO2 nanoparticles could interfere with the balance of the immune system and dynamic of gut microbiome, which may result in low-grade intestinal inflammation and aggravated immunological response to external stimulus, thus introducing potential health risk.”

FDA’s response

Currently, titanium dioxide as a food additive is classified as GRAS, or “generally recognized as safe.” 

Stability and darkening:

In addition to consistency, manufacturers must also consider the cost implications of buff percentage. Higher levels of coating on titanium dioxide particles can increase production costs, as more coating materials are required. However, a lower buff percentage may lead to a lower quality product that does not meet the needs of customers. Balancing the cost and quality considerations of buff percentage is a key challenge for manufacturers in the titanium dioxide industry.

Assessment of skin penetration and biohazard in vivo

0.1% Max

Nowadays, the use of nanoparticles in pharmaceutical and cosmetic products has increased. In the last case, nano-sized components are used without proper characterization of their effects, leading to unwanted and dangerous consequences for the users [1,2].

Main products are titanium dioxide LR-982, titanium dioxide LR-108, titanium dioxide LR-996, LR-895 and other products.

There is also some evidence to suggest that exposure to titanium dioxide nanoparticles may be harmful or toxic to the environment, including aquatic life and other organisms. The production and disposal of the mineral may also release pollutants, such as carbon dioxide and sulfur dioxide, into the air and water.

Total Zinc (as ZnS)