Colorectal tumors and preneoplastic lesions
Key benefits for stakeholders

≤0.4
The so-called “barrier effect” makes it possible to achieve good anti-corrosion protection in primers.
After conducting a review of all the relevant available scientific evidence, EFSA concluded that a concern for genotoxicity of TiO2 particles cannot be ruled out. Based on this concern, EFSA’s experts no longer consider titanium dioxide safe when used as a food additive. This means that an Acceptable Daily Intake (ADI ) cannot be established for E171.

The price trendss for titanium dioxide kept on the lower side of the scale during the first half of 2023. As the paint and coatings industries reduced their offtakes, the abundant supply of the product in the market led to a fall in prices. The prices also suffered from falling energy costs and declining freight charges. Further, the rising speculations of a global recession caused manufacturers to participate actively in destocking.
Fig. 9. Selected images of damaged skin treated with P25TiO2NPs 10% (left) and healthy skin treated with VitaminB2@P25TiO2NPs 10% (right).

titanium dioxide gravimetric analysis. This is done by comparing the weight of the precipitate to the weight of the original sample. By knowing the molecular weight of titanium dioxide, the percentage of the compound in the sample can be determined.
Animal studies show exposure to titanium dioxide is linked to immunotoxicity, inflammation and neurotoxicity.
According to the EFSA's Expert Panel on Food Additives and Flavorings 2021 opinion regarding titanium dioxide, it could not rule out a concern for genotoxicity from ingestion of the material based on a perceived gap in data on this risk, which serves as the basis for current ban, said a March report on the decision.



