The safety of the food additive E 171 was re-evaluated by the EFSA ANS Panel in 2016 in the frame of Regulation (EU) No 257/2010, as part of the re-evaluation programme for food additives authorised in the EU before 20 January 2009.

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Titanium dioxide is added to some food packaging to preserve the shelf life of a product.
History
Barium sulfide is produced by carbothermic reduction of barium sulfate. Zinc sulfate is obtained from a variety of zinc products, often waste, by treatment with sulfuric acid.

Top 10 Chinese TiO2 exporters in 2016
Certificate of Analysis (Lithopone B301, Lithopone B311 powder TDS)
Blanc de Comines, 27 per cent zinc sulphide, 70.5 per cent barium sulphate, 2.5 per cent zinc carbonate.
FDA’s response
5.It is widely used in the paint industry to improve the durability of curing of zinc-white coatings and to prepare various color paints.
Asia
R-996:
UV–vis spectra were carried out in the supernatant of both vitamins@P25TiO2NPs samples after centrifugation to measure the amount of unbound vitamin. Standard curves at 375 nm and 255 nm were done for vitamin B2 and C, respectively, using a Synergy BioTeK multi-mode microplate reader.
